WHOLE TRANSCRIPTOME ANALYSIS TO EXPLORE THE IMPAIRED IMMUNOLOGICAL FEATURES IN CRITICALLY ILL ELDERLY PATIENTS WITH SEPSIS

Whole transcriptome analysis to explore the impaired immunological features in critically ill elderly patients with sepsis

Abstract Background Sepsis is a frequent complication in critically ill patients, is highly heterogeneous and is associated with high morbidity and mortality rates, especially in the elderly population.Utilizing RNA sequencing (RNA-Seq) to analyze biological pathways is widely used in clinical and molecular genetic studies, but studies in elderly p

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Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air)

Abstract Background The present study was designed to test the hypothesis that chronic very mild prenatal carbon monoxide (CO) exposure (25 parts per million) subverts the normal development of the rat cerebellar cortex.Studies at this chronic low CO exposure over the earliest periods of mammalian development have not been performed to date.Pregnan

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The EBITDA disclosed by companies listed on Brazil stock exchange (B3): locations, types, and occurrence count

Purpose: To identify the types of EBITDA and locations disclosed by publicly traded companies in Brazil.Methodology: The study is documental, with data from the annual reports of Brazilian listed companies, using statistical techniques of univariate descriptive analysis.Results: 87.7% of the sample (336 companies) disclosed some form of EBITDA.Of t

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